Effectiveness of local application of antiseptic with octenidin dihydrochloride molecule in smoking women with ASC-US and LSIL

This article presents the results of our own experience topical use Prodexin antiseptic that is contained an octenidine dihydrochloride molecule as a monotherapy for ASC-US and LSIL cervical pathology (identified with in fluid cytology) associated human papillomavirus smoking women.Study objective: To study efficacy application vaginal suppositories treatment women LSIL.Materials methods. The involved 45 female smokers identified or LSIL. complex examination included: Pap test based on liquid cytology, testing 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68 types quantitative format, screening causes vaginitis, extended colposcopy to exclude intraepithelial neoplasia II+. were used according 3-month regimen (20 daily, then 10 two consecutive cycles).Results. Clinical laboratory assessment therapy effectiveness has convincingly shown its positive effect vagina cervix. Treatment microbiota normalization, colposcopic picture improvement changes smear NILM I II. Regress was recorded 20 (86.9%) patients 15 (68.8%) LSIL.Conclusions. allows avoid worsening situation prevent progression HSIL. Proposed had no side effects, convenient did not require additional visits doctor during therapy. control over viral load been postponed 6–12 months from beginning examination, will be second stage work.